Methodology

 

2014-01-00021B Fig3v10_reduced

Functional and Comparative Genomics
We use a combination of comparative and functional genomics to understand how behavioral changes are encoded in the genome and how genomes diverge during speciation.

 

 

Aedes aegypti

Behavior
We use laboratory behavior assays to precisely quantify the behavior of natural mosquito populations.

 

 

 

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Molecular Biology and Transgenics
We use molecular biology approaches including bacterial cloning, immunohistochemistry, and targeted mutagenesis to characterize the function of genes and genetic changes underlying behavior and evolution.

 

 

2014-01-00021A Fig4v15

 Electrophysiology and Neural Imaging
We use electrophysiological recording to characterize the binding profiles of olfactory sensory neurons and the receptors they express. We are also developing the genetic reagents necessary to image activity in the central nervous system with the genetically encoded calcium indicator GCaMP.